Vardenafil(Levitra) for ED Improves Couple Satisfaction Level

By Aude Lecrubier

PARIS (Reuters Health) april 07 - A 12-week multicenter, double-blind study, presented at the 21st meeting of the European Urology firm, demonstrated that vardenafil (Levitra) for erectile dysfunction (ED) significantly improves rates of penetration and intercourse completion compared with placebo in PDE-5-naive men, and significantly improves Companion satisfaction extremely.

“In my opinion over the years, trials of erectile dysfunction have not attributed Sufficiently control to the couple Element. Our new trial shows that successful therapy for erectile dysfunction with Levitra benefits both partners,” primary investigator Dr. David Edwards of White House Surgery, Chipping Norton, UK, said. (more…)

Tadalafil(Cialis) Improves Erectile Function in Men With Spinal Cord Injury

Susan Jeffrey

Results of a randomized trial show that use of tadalafil (Cialis, Eli Lilly) improved erectile function and was well tolerated by men with erectile dysfunction (ED) secondary to traumatic spinal cord injury (SCI).

Results of the trial were published online September 10 and scheduled for the November issue of the Archives of Neurology.

“As in other ED studies that included patients who were difficult to treat owing to preexisting conditions (eg, prostatectomy, diabetes mellitus), tadalafil was efficacious for the treatment of ED after a traumatic SCI,” the researchers, with first author Franc,ois Giuliano MD, PhD, from Raymond Poincare’ Infirmary, in Garches, France, conclude. “On-demand treatment with tadalafil (10 mg or 20 mg) may help improve the sex lives of patients with ED and SCI and their partners.” (more…)

Sildenafil(Viagra) Increases, Tadalafil(Cialis) Decreases Sperm Motility

NEW YORK (Reuters Health) Nov 12 - Sildenafil(Viagra) keenly increases sperm motility in young infertile men, Italian researchers Announcement in the October issue of Fertility and Sterility. The opposite is true for tadalafil(Cialis).

Dr. Giorgio Pomara and colleagues at the University of Pisa in Rome, administered a single 50 mg Potion of sildenafil or 20 mg of tadalafil to 18 young infertile men in a randomized, double-blind crossover study with a two-week washout period between treatment arms. (more…)

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Erectile dysfunction (ED)

Erectile dysfunction (ED) is the inability of a man to carry through or maintain an erection sufficient for his sexual needs or the needs of his Companion.Most men experience this at some point in their lives, usually by lifetime 40, and are not psychologically affected by it.

Some men, however, experience chronic, outright erectile dysfunction (impotence), and others, partial or miniature erections. Frequent erectile dysfunction can element emotional and relationship problems, and Frequently leads to diminished self-esteem. Erectile dysfunction has many causes, most of which are treatable, and is not an inevitable consequence of aging.

Incidence and Prevalence
The term “erectile dysfunction” can mean the inability to carry through erection, an inconsistent facility to do so, or the facility to carry through only miniature erections. These various definitions make estimating the incidence of erectile dysfunction difficult. According to the National Institutes of Health in 2002, an estimated 15 million to 30 million men in the USA experience chronic erectile dysfunction.

According to the National Ambulatory Medical apprehension Survey (NAMCS), enclosing 22 out of every 1000 men in the USA sought medical concern for ED in 1999.

Incidence of the Chaos increases with lifetime. Chronic ED affects approximately 5% of men in their 40s and 15–25% of men by the lifetime of 65. Transient ED and inadequate erection alter as many as 50% of men between the ages of 40 and 70.

Diseases (e.g., diabetes, kidney disease, alcoholism, atherosclerosis) chronicle for as many as 70% of chronic ED cases and psychological factors (e.g., stress, anxiety, depression) may chronicle for 10–20% of cases. Between 35 and 50% of men with diabetes experience ED.

Anatomy of the Penis
The internal structure of the penis consists of two cylinder-shaped vascular tissue bodies (corpora cavernosa) that run throughout the penis; the urethra (tube for expelling urine and ejaculate); erectile tissue surrounding the urethra; two main arteries; and several veins and nerves. The longest part of the penis is the shaft, extreme of which is the head, or glans penis. The opening at the tip of the glans, which allows for urination and ejaculation, is the meatus.

Physiology of Erection
The physiological process of erection begins in the brain and involves the nervous and vascular systems. Neurotransmitters in the brain (e.g., epinephrine, acetylcholine, nitric oxide) are some of the chemicals that initiate it. Physical or psychological stimulation (arousal) causes nerves to send messages to the vascular system, which results in significant blood flow to the penis. Two arteries in the penis supply blood to erectile tissue and the corpora cavernosa, which develop into engorged and expand as a Conclusion of increased blood flow and pressure.

in that blood must stay in the penis to maintain rigidity, erectile tissue is enclosed by fibrous elastic sheathes (tunicae) that cinch to prevent blood from leaving the penis during erection. When stimulation ends, or following ejaculation, pressure in the penis decreases, blood is released, and the penis resumes its normal shape.